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Self-Assembled DNA Nanocentipede as Multivalent Vehicle for Enhanced Delivery of CpG Oligonucleotides

Abstract

We reported a self-assembled nanocentipede as multivalent vehicle for delivery of immunostimulatory CpG ODNs. The multivalent vehicle could be internalized by RAW264.7 cells and stimulated the secretion of large amounts of cytokines, successively induced effective apoptosis of cancer cells.

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Publication details

The article was received on 13 Feb 2017, accepted on 18 Apr 2017 and first published on 18 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC01128H
Citation: Chem. Commun., 2017, Accepted Manuscript
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    Self-Assembled DNA Nanocentipede as Multivalent Vehicle for Enhanced Delivery of CpG Oligonucleotides

    W. Li, L. Luo, J. Huang, Q. Wang, J. Liu, X. Xiao, H. Fang, X. Yang and K. Wang, Chem. Commun., 2017, Accepted Manuscript , DOI: 10.1039/C7CC01128H

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