Jump to main content
Jump to site search

Issue 26, 2017
Previous Article Next Article

Ru(II)-Pheox-catalyzed Si–H insertion reaction: construction of enantioenriched carbon and silicon centers

Author affiliations

Abstract

We established a highly enantioselective Si–H insertion reaction to construct chiral centers at the carbon and silicon atoms, using a Ru(II)-pheox catalyst. The catalytic asymmetric Si–H insertion reaction of α-methyl-α-diazoesters proceeded smoothly with excellent stereoinduction at both the neighboring carbon and silicon atoms (up to 99% yield and 99% ee).

Graphical abstract: Ru(ii)-Pheox-catalyzed Si–H insertion reaction: construction of enantioenriched carbon and silicon centers

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Feb 2017, accepted on 07 Mar 2017 and first published on 09 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC01070B
Citation: Chem. Commun., 2017,53, 3753-3756
  •   Request permissions

    Ru(II)-Pheox-catalyzed Si–H insertion reaction: construction of enantioenriched carbon and silicon centers

    Y. Nakagawa, S. Chanthamath, I. Fujisawa, K. Shibatomi and S. Iwasa, Chem. Commun., 2017, 53, 3753
    DOI: 10.1039/C7CC01070B

Search articles by author

Spotlight

Advertisements