Jump to main content
Jump to site search


Reversible crystal-to-crystal chiral resolution: making/breaking non-bonding S⋯O interactions

Author affiliations

Abstract

An achiral organic molecule adopts a chiral conformation, crystallizing in two morphologies: a racemic form, stable <70 °C, and a homochiral form, stable ≥70 °C. Upon seeding, crystal-to-crystal phase transitions occur reversibly between the racemic and chiral forms. Liquid-to-solid chiral crystallization is observed >90% of the time from the melt.

Graphical abstract: Reversible crystal-to-crystal chiral resolution: making/breaking non-bonding S⋯O interactions

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 03 Feb 2017, accepted on 13 Mar 2017, published on 13 Mar 2017 and first published online on 13 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC00907K
Citation: Chem. Commun., 2017, Advance Article
  •   Request permissions

    Reversible crystal-to-crystal chiral resolution: making/breaking non-bonding S⋯O interactions

    R. A. Mayo, D. J. Sullivan, T. A. P. Fillion, S. W. Kycia, D. V. Soldatov and K. E. Preuss, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC00907K

Search articles by author