Jump to main content
Jump to site search

Issue 25, 2017
Previous Article Next Article

Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes

Author affiliations

Abstract

β-(1,3)-Glucans exhibit immunomodulatory and anti-tumor effects. Since the isolation of pure β-(1,3)-glucan oligosaccharides from natural sources is complicated, especially when certain branching patterns are desired, chemical synthesis is frequently the only means of accessing these molecules. We report the iterative automated glycan assembly (AGA) of conjugation-ready linear and branched β-(1,3)-glucan oligosaccharides.

Graphical abstract: Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Jan 2017, accepted on 07 Mar 2017 and first published on 07 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC00520B
Citation: Chem. Commun., 2017,53, 3591-3594
  • Open access: Creative Commons BY license
  •   Request permissions

    Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes

    M. W. Weishaupt, H. S. Hahm, A. Geissner and P. H. Seeberger, Chem. Commun., 2017, 53, 3591
    DOI: 10.1039/C7CC00520B

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements