Jump to main content
Jump to site search

Issue 24, 2017
Previous Article Next Article

Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine and amide source

Author affiliations

Abstract

The catalytic asymmetric bromoamination of chalcones with N-bromosuccinimide as both bromine and amide source was realized by using a chiral N,N′-dioxide-Sc(NTf2)3 complex as an efficient catalyst. The corresponding chiral bromoamination products were obtained in high yields with high dr and good ee values (up to 92% yield, 93 : 7 dr and 97% ee) under mild reaction conditions.

Graphical abstract: Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine and amide source

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Jan 2017, accepted on 28 Feb 2017 and first published on 28 Feb 2017


Article type: Communication
DOI: 10.1039/C7CC00470B
Citation: Chem. Commun., 2017,53, 3462-3465
  •   Request permissions

    Chiral N,N′-dioxide-Sc(NTf2)3 complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine and amide source

    Z. Wang, L. Lin, P. Zhou, X. Liu and X. Feng, Chem. Commun., 2017, 53, 3462
    DOI: 10.1039/C7CC00470B

Search articles by author

Spotlight

Advertisements