Jump to main content
Jump to site search

Issue 26, 2017
Previous Article Next Article

A catalytic enantioselective approach to tetrol bearing vicinal all-carbon quaternary stereogenic centers

Author affiliations

Abstract

The first highly enantioselective catalytic protocol for selective manipulation of tetrol benzylidene acetals through chiral phosphoric acid mediated oxidative desymmetrization is reported. This efficient approach provides a general access to vicinal all-carbon quaternary stereogenic center structural motifs, as well as structures containing vicinal tertiary and quaternary stereocenters enantioselectively. The synthetic utility has been furthermore demonstrated by transformations and gram-scale processes.

Graphical abstract: A catalytic enantioselective approach to tetrol bearing vicinal all-carbon quaternary stereogenic centers

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 18 Jan 2017, accepted on 08 Mar 2017, published on 08 Mar 2017 and first published online on 08 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC00457E
Citation: Chem. Commun., 2017,53, 3737-3740
  •   Request permissions

    A catalytic enantioselective approach to tetrol bearing vicinal all-carbon quaternary stereogenic centers

    H. Yang, K. Cao and W. Zheng, Chem. Commun., 2017, 53, 3737
    DOI: 10.1039/C7CC00457E

Search articles by author