Issue 28, 2017

Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Abstract

The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.

Graphical abstract: Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Supplementary files

Article information

Article type
Communication
Submitted
16 Jan 2017
Accepted
15 Mar 2017
First published
15 Mar 2017

Chem. Commun., 2017,53, 4022-4025

Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

L. He, S. Sarkar, A. Barras, R. Boukherroub, S. Szunerits and D. Mandler, Chem. Commun., 2017, 53, 4022 DOI: 10.1039/C7CC00381A

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