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DNA-spheres decorated with magnetic nanocomposites based on terminal transfer reactions for versatile target detection and cellular targeted drug delivery

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Abstract

We present an elegant approach to make a magnetic nanoparticle (MNP) conjugated DNA-sphere (MNP/DNA-SP) which is integrated with disulfide (MNP/DS-SP) or an aptamer (MNP/sgc8-SP) for GSH detection, selective cancer cell recognition, effective drug delivery, and bioimaging.

Graphical abstract: DNA-spheres decorated with magnetic nanocomposites based on terminal transfer reactions for versatile target detection and cellular targeted drug delivery

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Publication details

The article was received on 13 Jan 2017, accepted on 30 Mar 2017 and first published on 06 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC00310B
Citation: Chem. Commun., 2017, Advance Article
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    DNA-spheres decorated with magnetic nanocomposites based on terminal transfer reactions for versatile target detection and cellular targeted drug delivery

    Y. Guo, Y. Wang, S. Li, L. Niu, D. Wei and S. Zhang, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C7CC00310B

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