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Issue 21, 2017
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Reversible DNA micro-patterning using the fluorous effect

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Abstract

We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.

Graphical abstract: Reversible DNA micro-patterning using the fluorous effect

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Publication details

The article was received on 12 Jan 2017, accepted on 15 Feb 2017 and first published on 23 Feb 2017


Article type: Communication
DOI: 10.1039/C7CC00288B
Citation: Chem. Commun., 2017,53, 3094-3097
  • Open access: Creative Commons BY license
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    Reversible DNA micro-patterning using the fluorous effect

    G. E. Flynn, J. M. Withers, G. Macias, J. R. Sperling, S. L. Henry, J. M. Cooper, G. A. Burley and A. W. Clark, Chem. Commun., 2017, 53, 3094
    DOI: 10.1039/C7CC00288B

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