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Issue 21, 2017
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Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

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Abstract

The novel property of reversible regulation of parallel type G-quadruplexes with moderate temperature changes was discovered in thermoresponsive hydrogels using a universal chiroptical spectrophotometer 1 (UCS-1). This study is the first to report the regulation of the ssDNA steric structure by using a poly(N-isopropylacrylamide) (PNIPAAm) gel.

Graphical abstract: Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

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Publication details

The article was received on 12 Jan 2017, accepted on 22 Feb 2017 and first published on 22 Feb 2017


Article type: Communication
DOI: 10.1039/C7CC00279C
Citation: Chem. Commun., 2017,53, 3142-3144
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    Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel

    E. Hasuike, A. M. Akimoto, R. Kuroda, K. Matsukawa, Y. Hiruta, H. Kanazawa and R. Yoshida, Chem. Commun., 2017, 53, 3142
    DOI: 10.1039/C7CC00279C

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