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Issue 24, 2017
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In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on membranes

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Abstract

The first in vitro selection of binding peptides against artificial lipid membranes from a random peptide library using an in vitro display method (cDNA display) is reported. The selected peptide, LB-1, has both amphiphilic and cationic regions, and proteins fused to LB-1 can be immobilized on the liposome surface.

Graphical abstract: In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on membranes

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Publication details

The article was received on 06 Jan 2017, accepted on 16 Feb 2017 and first published on 08 Mar 2017


Article type: Communication
DOI: 10.1039/C7CC00099E
Citation: Chem. Commun., 2017,53, 3458-3461
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    In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on membranes

    S. Kobayashi, T. Terai, Y. Yoshikawa, R. Ohkawa, M. Ebihara, M. Hayashi, K. Takiguchi and N. Nemoto, Chem. Commun., 2017, 53, 3458
    DOI: 10.1039/C7CC00099E

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