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Issue 25, 2017
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Characterization of DNA duplex unzipping through a sub-2 nm solid-state nanopore

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Abstract

Herein, the unzipping and translocation of DNA duplexes through a sub-2 nm silicon nitride (SiNx) solid-state nanopore have been demonstrated by well-resolved three-level blockades. In order to examine our observations, we applied a simple model which is applicable to the unzipping and translocation processes of DNA duplexes through solid-state nanopores. The generation of these highly recognizable signatures is an important step towards the real applications of solid-state nanopores in complex samples.

Graphical abstract: Characterization of DNA duplex unzipping through a sub-2 nm solid-state nanopore

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Publication details

The article was received on 04 Jan 2017, accepted on 28 Feb 2017, published on 28 Feb 2017 and first published online on 28 Feb 2017


Article type: Communication
DOI: 10.1039/C7CC00060J
Citation: Chem. Commun., 2017,53, 3539-3542
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    Characterization of DNA duplex unzipping through a sub-2 nm solid-state nanopore

    Y. Lin, X. Shi, S. Liu, Y. Ying, Q. Li, R. Gao, F. Fathi, Y. Long and H. Tian, Chem. Commun., 2017, 53, 3539
    DOI: 10.1039/C7CC00060J

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