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Issue 29, 2017
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C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

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Abstract

C-Phycocyanin (CPC) as a tumour-associated macrophage (TAM)-targeted photosensitiser has been first proved, and used as a vehicle of zinc phthalocyanine (ZnPc) to fabricate a ZnPc–CPC conjugate, which exhibits an efficient in vitro photodynamic activity, and selectively accumulates in tumour sites probably due to the affinity to TAM.

Graphical abstract: C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

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Publication details

The article was received on 30 Nov 2016, accepted on 13 Mar 2017 and first published on 20 Mar 2017


Article type: Communication
DOI: 10.1039/C6CC09541K
Citation: Chem. Commun., 2017,53, 4112-4115
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    C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

    D. Wan, B. Zheng, M. Ke, J. Duan, Y. Zheng, C. Yeh and J. Huang, Chem. Commun., 2017, 53, 4112
    DOI: 10.1039/C6CC09541K

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