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Transcriptional regulatory proteins as biosensing tools

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Abstract

We have developed sensing systems employing different classes of transcriptional regulatory proteins genetically and chemically modified to incorporate a fluorescent reporter molecule for detection of arsenic, hydroxylated polychlorinated biphenyls (OH-PCBs), and cyclic AMP (cAMP). These are the first examples of optical sensing systems based on transcriptional regulatory proteins.

Graphical abstract: Transcriptional regulatory proteins as biosensing tools

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Publication details

The article was received on 30 Nov 2016, accepted on 02 May 2017 and first published on 02 May 2017


Article type: Communication
DOI: 10.1039/C6CC09512G
Citation: Chem. Commun., 2017, Advance Article
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    Transcriptional regulatory proteins as biosensing tools

    K. Turner, S. Joel, J. Feliciano, A. Feltus, P. Pasini, D. Wynn, P. Dau, E. Dikici, S. K. Deo and S. Daunert, Chem. Commun., 2017, Advance Article , DOI: 10.1039/C6CC09512G

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