Issue 12, 2017

Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

Abstract

The formation of stable blood clots or hemostasis is essential to prevent major blood loss and death from excessive bleeding. However, the body's own coagulation process is not able to accomplish timely hemostasis without the assistance of hemostatic agents. For developing novel topical hemostatic agents, tissue adhesives and sealants, it is necessary to understand the coagulation process and the hemostasis mechanism of different materials. Among hemostatic materials, polysaccharides are naturally derived polymers having excellent biodegradable and biocompatible properties. This review provides an overview of polysaccharide-based hemostatic materials and agents, including their advantages and drawbacks in hemostatic applications. Furthermore, polysaccharide-based hemostatic materials with anti-microbial and healing functions are also introduced.

Graphical abstract: Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

Article information

Article type
Review Article
Submitted
25 Jun 2017
Accepted
20 Sep 2017
First published
20 Sep 2017

Biomater. Sci., 2017,5, 2357-2368

Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

X. Yang, W. Liu, N. Li, M. Wang, B. Liang, I. Ullah, A. Luis Neve, Y. Feng, H. Chen and C. Shi, Biomater. Sci., 2017, 5, 2357 DOI: 10.1039/C7BM00554G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements