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Issue 8, 2017
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From molecules to macrostructures: recent development of bioinspired hard tissue repair

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Abstract

Enamel, dentin and bone are calcified hard tissues in the human body that play significant roles in food mastication and movement support. Generally, hard tissues lack the ability of self-repair, except for the regeneration ability of bone for small-scale defects. Fabrication of man-made repair materials is therefore highly demanded. In this review, following a bioinspired strategy, we describe the composition and multiscale structures of different hard tissues, and highlight the key points for the reconstruction of hard tissues. Finally, bioinspired tissue repair techniques ranging from molecule-induced mineralization, to microscale assembly to macroscaffold fabrication are summarised.

Graphical abstract: From molecules to macrostructures: recent development of bioinspired hard tissue repair

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Publication details

The article was received on 25 Mar 2017, accepted on 10 Jul 2017 and first published on 10 Jul 2017


Article type: Review Article
DOI: 10.1039/C7BM00247E
Citation: Biomater. Sci., 2017,5, 1435-1449
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    From molecules to macrostructures: recent development of bioinspired hard tissue repair

    C. Ding, Z. Chen and J. Li, Biomater. Sci., 2017, 5, 1435
    DOI: 10.1039/C7BM00247E

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