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The scaffold microenvironment for stem cell based bone tissue engineering

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Abstract

Bone tissue engineering uses the principles and methods of engineering and life sciences to study bone structure, function and growth mechanism for the purposes of repairing, maintaining and improving damaged bone tissue. Scaffolds not only provide structural support for stem cells in cell adhesion and proliferation and bone formation, but also serve as a microenvironment for guiding stem cell differentiation and tissue regeneration and for controlling tissue structure. This review presents the research status of the scaffold microenvironment for bone-related stem cells based on bone tissue engineering. Scaffold materials and the stem cell microenvironment are described in this review, and the existing shortcomings are also simply mentioned.

Graphical abstract: The scaffold microenvironment for stem cell based bone tissue engineering

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Publication details

The article was received on 22 Feb 2017, accepted on 09 Apr 2017 and first published on 10 Apr 2017


Article type: Review Article
DOI: 10.1039/C7BM00146K
Citation: Biomater. Sci., 2017, Advance Article
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    The scaffold microenvironment for stem cell based bone tissue engineering

    Z. Hao, Z. Song, J. Huang, K. Huang, A. Panetta, Z. Gu and J. Wu, Biomater. Sci., 2017, Advance Article , DOI: 10.1039/C7BM00146K

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