Issue 5, 2017

Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines

Abstract

Cyclopeptides have been recently used successfully as carriers for the multivalent presentation of carbohydrate and peptide antigens in immunotherapy. Beside their synthetic versatility, these scaffolds are indeed interesting due to their stability against enzyme degradation and low immunogenicity. This mini-review highlights the recent advances in the utilization of cyclopeptides to prepare fully synthetic vaccines prototypes against cancers and pathogens.

Graphical abstract: Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines

Article information

Article type
Minireview
Submitted
25 Jan 2017
Accepted
03 Mar 2017
First published
09 Mar 2017
This article is Open Access
Creative Commons BY-NC license

Biomater. Sci., 2017,5, 953-965

Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines

C. Pifferi, N. Berthet and O. Renaudet, Biomater. Sci., 2017, 5, 953 DOI: 10.1039/C7BM00072C

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