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Issue 8, 2017
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Glutathione-responsive paclitaxel dimer nanovesicles with high drug content

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Abstract

Paclitaxel dimer-based nanovesicles, with an ultrahigh drug content, have been prepared through a nanoprecipitation method. The as-formed nanovesicles exhibit improved paclitaxel solubility, prominent colloid stability, GSH-triggered disassembly, effective cellular uptake and comparable cytotoxicity to Taxol.

Graphical abstract: Glutathione-responsive paclitaxel dimer nanovesicles with high drug content

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Publication details

The article was received on 18 Jan 2017, accepted on 02 Feb 2017 and first published on 13 Feb 2017


Article type: Communication
DOI: 10.1039/C7BM00052A
Citation: Biomater. Sci., 2017,5, 1517-1521
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    Glutathione-responsive paclitaxel dimer nanovesicles with high drug content

    Q. Pei, X. Hu, J. Zhou, S. Liu and Z. Xie, Biomater. Sci., 2017, 5, 1517
    DOI: 10.1039/C7BM00052A

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