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Issue 44, 2017
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Electrochemical nanostructure platform for the analysis of glutathione in the presence of uric acid and tryptophan

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Abstract

In this work, a NiO–CNT nanocomposite and 2-(3,4-dihydroxyphenethyl)isoindoline-1,3-dione (DPID) were used as modifiers for the modification of a carbon paste electrode (DPID/NiO–CNT/CPE) for the electro-catalytic analysis of glutathione (GSH). The electro-catalytic interaction between DPID and GSH on the surface of the DPID/NiO–CNT/CPE was used as a new way for the analysis of GSH. GSH can be detected on the surface of the DPID/NiO–CNT/CPE in the concentration ranges of 0.03–10.0 and 10.0–200.0 μM with a detection limit of 0.015 μM. The DPID/NiO–CNT/CPE facilitated the simultaneous analysis of glutathione (GSH) in the presence of uric acid (UA) and tryptophan (Trp). The DPID/NiO–CNT/CPE showed high performance ability for GSH analysis in real samples.

Graphical abstract: Electrochemical nanostructure platform for the analysis of glutathione in the presence of uric acid and tryptophan

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Publication details

The article was received on 27 Aug 2017, accepted on 07 Oct 2017 and first published on 09 Oct 2017


Article type: Paper
DOI: 10.1039/C7AY02057K
Citation: Anal. Methods, 2017,9, 6228-6234
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    Electrochemical nanostructure platform for the analysis of glutathione in the presence of uric acid and tryptophan

    H. Karimi-Maleh, A. Bananezhad, M. R. Ganjali and P. Norouzi, Anal. Methods, 2017, 9, 6228
    DOI: 10.1039/C7AY02057K

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