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Electrochemical nanostructure platform for analysis of glutathione in the presence of uric acid and tryptophan

Abstract

In this work, NiO-CNT nanocomposite and 2-(3,4 dihydroxyphenethyl) isoindoline-1,3-dione (DPID) were used as modifiers for modification of carbon paste electrode (DPID/NiO-CNT/CPE) for electro-catalytic analysis of glutathione (GSH). The electro-catalytic interaction between DPID and GSH at a surface of DPID/NiO-CNT/CPE was used as a new way for analysis of GSH. The GSH can be detected at a surface of DPID/NiO-CNT/CPE in the concentration rage 0.03-10.0 and 10.0- 200.0 μM with detection limit 0.015 μM. The DPID/NiO-CNT/CPE facilitated the simultaneous analysis of glutathione (GSH) in the presence of uric acid (UA) and tryptophan (Trp). The DPID/NiO-CNT/CPE showed high performance ability for GSH analysis in real samples.

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Publication details

The article was received on 27 Aug 2017, accepted on 07 Oct 2017 and first published on 09 Oct 2017


Article type: Paper
DOI: 10.1039/C7AY02057K
Citation: Anal. Methods, 2017, Accepted Manuscript
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    Electrochemical nanostructure platform for analysis of glutathione in the presence of uric acid and tryptophan

    H. Karimi-Maleh, A. Bananejad, M. R. Ganjali and P. Norouzi, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C7AY02057K

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