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Issue 37, 2017
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Frequency characterization of flow magnitude and phase in resonant microfluidic circuits

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Abstract

The classic electric-hydraulic analogy has been utilized to create microfluidic equivalents of electrical circuits that find applications in lab-on-a-chip and microTAS devices. Despite the continued use of the analogy in pedagogy and for scientific discovery, a thorough experimental validation of this classic analogy using standard electrical characterization techniques has not been performed. In this work, we present two independent methods for assessing the magnitude and phase of harmonic flow in microfluidic networks with deformable features: (1) a custom stroboscopic epifluorescence setup for measuring flow in the channel via bead tracking, and (2) a novel diaphragm-lens optical vibration sensor for estimating flow in the deformable feature. We show that magnitude and phase frequency responses quantitatively match model predictions for series and parallel resonant RLC microfluidic devices. Through this work, we demonstrate the tools and techniques for simultaneous measurement of flow magnitude and phase in microfluidic resonant devices with the goal to further corroborate the electric analogy for two archetypal electrical circuits and to allow quantitative characterization of more complex circuits in the future.

Graphical abstract: Frequency characterization of flow magnitude and phase in resonant microfluidic circuits

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Publication details

The article was received on 11 Jul 2017, accepted on 04 Sep 2017 and first published on 06 Sep 2017


Article type: Paper
DOI: 10.1039/C7AY01699A
Citation: Anal. Methods, 2017,9, 5425-5432
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    Frequency characterization of flow magnitude and phase in resonant microfluidic circuits

    R. Jain, R. B. Darling and B. Lutz, Anal. Methods, 2017, 9, 5425
    DOI: 10.1039/C7AY01699A

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