Jump to main content
Jump to site search

Issue 32, 2017
Previous Article Next Article

Square-wave adsorptive anodic stripping voltammetric determination of ramipril using an electrochemical sensor based on nanostructured carbon black

Author affiliations

Abstract

A novel and alternative electroanalytical method for the determination of ramipril (RAM) using a glassy carbon electrode (GCE) modified with nanostructured carbon black (CB) is reported. The electrochemical sensor was obtained by a simple drop coating strategy, and the designed architecture consisted of a GCE modified with CB within a dihexadecylphosphate film. The remarkable electrocatalytic activity of CB towards RAM electrooxidation was verified, and from different electrochemical assays, the number of electrons involved in the RAM oxidation was determined and, therefore, an electrooxidation reaction for RAM molecules was proposed. Under optimised experimental conditions, RAM was determined by square-wave adsorptive anodic stripping voltammetry. The analytical curve of RAM was linear from 1.98 × 10−6 to 2.42 × 10−5 mol L−1, with a limit of detection of 4.27 × 10−7 mol L−1. The proposed voltammetric procedure was successfully applied for the determination of RAM in pharmaceutical products and biological samples.

Graphical abstract: Square-wave adsorptive anodic stripping voltammetric determination of ramipril using an electrochemical sensor based on nanostructured carbon black

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Jun 2017, accepted on 12 Jul 2017 and first published on 13 Jul 2017


Article type: Paper
DOI: 10.1039/C7AY01479A
Citation: Anal. Methods, 2017,9, 4680-4687
  •   Request permissions

    Square-wave adsorptive anodic stripping voltammetric determination of ramipril using an electrochemical sensor based on nanostructured carbon black

    T. A. Silva and O. Fatibello-Filho, Anal. Methods, 2017, 9, 4680
    DOI: 10.1039/C7AY01479A

Search articles by author

Spotlight

Advertisements