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The electrochemical sensor of dopamine based on polydopamine modified reduced graphene oxide anchored with tin dioxide and gold nanoparticles

Abstract

In the present work, polydopamine (PDA) modified reduced graphene oxide (pRGO)/SnO2/Au nanoparticles (NPs) were synthesized. The process is that SnO2/AuNPs was prepared through the redox reaction between reductive stannous (II) ions and oxidative auric (III) ions without any other reagents, then the pre-prepared graphene oxide (GO) was reduced and stabilized with the help of DA followed with decoration with SnO2/AuNPs. Morphology and structure of the hybrid nanomaterials were characterized by raman spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction analysis. Then we constructed the electrochemical sensors based on the hybrid nanomaterials for the determination of dopamine (DA). Cyclic voltammetry (CV) results showed that the hybrid nanomaterials had better sensing performance than pRGO/AuNPs and pRGO. Differential pulse voltammetry (DPV) showed that the separation of oxidation peak potentials for ascorbic acid (AA)-DA, uric acid (UA)-DA and UA-AA were about 200 mV, 100 mV and 300 mV, respectively. The linear range for the detection of DA was 0.008 µM to 20 µM with a coefficient of 0.9986. The detection limit was 5 nM (S/N=3). These indicate the selective and sensitive detection of DA. Finally, the constructed sensors were also applied to detect DA in human real samples.

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Supplementary files

Publication details

The article was received on 14 Apr 2017, accepted on 08 Aug 2017 and first published on 11 Aug 2017


Article type: Paper
DOI: 10.1039/C7AY00991G
Citation: Anal. Methods, 2017, Accepted Manuscript
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    The electrochemical sensor of dopamine based on polydopamine modified reduced graphene oxide anchored with tin dioxide and gold nanoparticles

    H. Zhao, X. Cui, X. Fang, Z. X. Li and H. Ren, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C7AY00991G

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