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Issue 34, 2017
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Immunoaffinity nanogold coupled with direct analysis in real time (DART) mass spectrometry for analytical toxicology

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Abstract

A rapid, definitive trace drug identification technique using nanogold surfaces with mass spectrometry was developed. High-surface area nanogold was deposited on gold wires and functionalized with antibodies. Effective drug capture in toxicological matrices with detection using LC-MS/MS and DART-MS/MS was demonstrated.

Graphical abstract: Immunoaffinity nanogold coupled with direct analysis in real time (DART) mass spectrometry for analytical toxicology

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Publication details

The article was received on 07 Apr 2017, accepted on 28 May 2017 and first published on 30 May 2017


Article type: Communication
DOI: 10.1039/C7AY00922D
Citation: Anal. Methods, 2017,9, 4954-4957
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    Immunoaffinity nanogold coupled with direct analysis in real time (DART) mass spectrometry for analytical toxicology

    K. M. Evans-Nguyen, T. L. Hargraves and A. N. Quinto, Anal. Methods, 2017, 9, 4954
    DOI: 10.1039/C7AY00922D

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