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Issue 34, 2017
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A coaxial extractive electrospray ionization source

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An extractive electrospray ionization (EESI) source design is presented to improve the reproducibility of the interactions occurring in EESI. This design uses three concentric capillaries to deliver the solvent, sample and nebulizing gas. Coaxial EESI was found to improve the inter-experiment variation by a factor of four and intra-run relative standard deviation by a factor of 2.4. Unlike most standard EESI designs, the device has the form factor of a standard electrospray emitter and can be used without any further instrument modifications.

Graphical abstract: A coaxial extractive electrospray ionization source

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Publication details

The article was received on 28 Mar 2017, accepted on 04 May 2017 and first published on 05 May 2017

Article type: Paper
DOI: 10.1039/C7AY00835J
Citation: Anal. Methods, 2017,9, 4997-5002
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    A coaxial extractive electrospray ionization source

    Kenneth. D. Swanson, Anne. L. Worth and Gary. L. Glish, Anal. Methods, 2017, 9, 4997
    DOI: 10.1039/C7AY00835J

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