Templated Electrodeposition of Vertically Aligned Copper Oxide Nanowire Arrays on 3D Ni Foam Substrates for Determination of Glucosamine in Pharmaceutical Caplet Samples
Copper oxide nanowires network electrode has been fabricated through electrodeposition procedure using mesoporous silica film as templates on Ni foam. The metal oxide nanostructures on Ni foam as a three dimensional electrode provide a very high surface area of electrode built on a low cost material. These electrodes features were considered with X-Ray diffraction (XRD), electrochemical impedance spectroscopy (EIS) and field emission scanning electron microscopy (FE-SEM). The electrochemical properties of the electrodes have also been studied. The prepared electrode was applied as a glucosamine sensor. The presented sensor possesses a high electrochemical active area and demonstrates high current density for glucosamine electro-oxidation. The presented sensor has a wide dynamic range for four order of magnitude to glucosamine in two linear range from 1.45 µM to 0.32 mM and 0.32 mM to 36.4 mM, with high sensitivity of 9.23 mA mM-1cm-2 in the first range and 1.85 mA mM-1cm-2 in the second range and low practical detection limit of 0.32 µM. It also showed outstanding long term stability, good reproducibility and accurate measurement in the pharmaceutical sample.