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C-Reactive Protein: A Major Inflammatory Biomarker

Abstract

Inflammatory biomarkers are released during tumour growth, and they are highly associated with the stages cancer progression. C-reactive protein is one of the widely studied marker proteins, which is associated with inflammation. CRP levels have been used to predict survival in patients with different cancers. The assimilation of CRP into prognostic models for cancers improves their predictive accuracy. The analysis of changes in CRP concentrations over time can allow predicting the tumour aggressiveness and treatment efficacy. Therefore CRP can be an important biomarker for cancer diagnosis, prognosis, and monitoring of treatment outcomes. This critical review focuses on the role of C-reactive protein in different types of cancers and its relation to the stages of cancer. This article also focuses on the recently reported methods for the detection of CRP.

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Publication details

The article was received on 17 Mar 2017, accepted on 16 May 2017 and first published on 17 May 2017


Article type: Critical Review
DOI: 10.1039/C7AY00711F
Citation: Anal. Methods, 2017, Accepted Manuscript
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    C-Reactive Protein: A Major Inflammatory Biomarker

    S. B. Nimse and M. D. Sonawane, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C7AY00711F

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