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A chemically reduced graphene oxide–Au nanocage composite for the electrochemical detection of dopamine and uric acid

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Abstract

Herein, a chemically reduced graphene oxide–Au nanocage (CRGO–AuNCs) composite was synthesized by electrostatic assembly of poly-diallyldimethylammonium chloride (PDDA)-modified CRGO and mercaptosuccinic acid (MSA)-modified Au nanocages. The product was characterized via AFM, TEM, EDS, and XRD. CRGO–AuNCs were then used to prepare an electrochemical sensor for the simultaneous detection of dopamine (DA) and uric acid (UA). Electrochemical investigations indicated that CRGO–AuNCs exhibited high peak currents for the oxidation of DA and UA. The composite-modified glass carbon electrode (CRGO–AuNC/GCE) displayed good selectivity and wide linear ranges for the simultaneous detection of DA (5–250 μM) and UA (5–150 μM).

Graphical abstract: A chemically reduced graphene oxide–Au nanocage composite for the electrochemical detection of dopamine and uric acid

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Publication details

The article was received on 14 Mar 2017, accepted on 29 May 2017 and first published on 30 May 2017


Article type: Paper
DOI: 10.1039/C7AY00677B
Citation: Anal. Methods, 2017, Advance Article
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    A chemically reduced graphene oxide–Au nanocage composite for the electrochemical detection of dopamine and uric acid

    W. Li, L. Ma, B. Wu, Y. Zhang and Z. Li, Anal. Methods, 2017, Advance Article , DOI: 10.1039/C7AY00677B

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