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A simple and efficient fluorescent probe for rapid detecting H2S in living cells and on agar gels

Abstract

A simple fluorescent probe (E)-1,3,3-trimethyl-2-(4-morpholinostyryl)-3H-indol-1-ium iodide (Mi) based on intramolecular charge transfer (ICT) was synthesized. The probe can sense hydrogen sulphide (H2S) rapidly and sensitively with low detection limit (15 nM). The reaction mechanism was investigated by fluorescence and mass spectra. Moreover, probe Mi was successfully used for fluorescent imaging of H2S in living cells, demonstrating its potential applications in biological science. Finally, agar gels based on Mi were fabricated, which could be acted as a solid optical sensor to detect H2S conveniently and efficiently.

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Publication details

The article was received on 24 Feb 2017, accepted on 27 Apr 2017 and first published on 04 May 2017


Article type: Paper
DOI: 10.1039/C7AY00499K
Citation: Anal. Methods, 2017, Accepted Manuscript
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    A simple and efficient fluorescent probe for rapid detecting H2S in living cells and on agar gels

    H. Li, Y. Li, B. Gu, W. Su, X. Duan, H. Xu, Z. Huang and S. Yao, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C7AY00499K

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