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Issue 13, 2017
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Aptamer-based biosensors for detection of lead(II) ion: a review

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Lead(II) ion (Pb2+) contamination can be accumulated along the food chain and cause a serious threat to public health. Plenty of research effort has thus been devoted to the development of fast, sensitive and selective biosensors for monitoring Pb2+. Aptamer especially Pb2+ based DNAzymes (obtained from a large DNA library via in vitro selection) and DNA molecules are highly selective for a number of metal ions. Therefore, aptamer-based biosensors have been extensively studied for Pb2+ ion detection with a high sensitivity. In this review, we explain the current progress of Pb2+ aptamer-based sensors mainly in three groups: fluorescent; colorimetric; and electrochemical biosensors.

Graphical abstract: Aptamer-based biosensors for detection of lead(ii) ion: a review

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Publication details

The article was received on 22 Feb 2017, accepted on 13 Mar 2017 and first published on 13 Mar 2017

Article type: Critical Review
DOI: 10.1039/C7AY00477J
Citation: Anal. Methods, 2017,9, 1976-1990
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    Aptamer-based biosensors for detection of lead(II) ion: a review

    D. Yang, X. Liu, Y. Zhou, L. Luo, J. Zhang, A. Huang, Q. Mao, X. Chen and L. Tang, Anal. Methods, 2017, 9, 1976
    DOI: 10.1039/C7AY00477J

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