A convenient approach for the determination multiple trace BPs by using in-syringe-assisted solid phase microextraction system packed with elastic spongy graphene rod coupled with HPLC
The elastic cylindrical three-dimensional porous spongy graphene rod (3D-PSGR) was synthetized by a facile one-step hydrothermal method and applied in a syringe system as a solid phase adsorbent for extraction of nine trace bisphenol analogs (BPs) from environmental samples. In this work, a simple sample pretreatment procedure in-syringe-assisted solid phase microextraction (ISA-SPME) was developed for the detection of nine BPs with HPLC. The full protocols for extraction and elution process were achieved in a syringe. After enrichment, the sample solution was slowly expelled from the syringe to leave the adsorbent with the analytes behind, which the analyte-enriched adsorbent was subsequently eluted by with drawing MeOH into the syringe, and then elution solution was injected in HPLC. The 3D-PSGR exhibits excellent cyclic stability and can be reused for eight consecutive cycles without significant loss of extraction efficiencies. The 3D-PSGR-ISA-SPME was successfully applied to the analysis of nine BPs in the river water and soil samples. The method detections limits (MDLs) were in the range of 0.39-3.97 ng mL-1 and the extraction recoveries of spiked samples were in the range of 96.5-102.6% with relative standard deviations (RSDs) of 2.11-4.27%. A convenient method is proposed for the analysis of nine trace BPs in environmental samples.