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Issue 14, 2017
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Green-fluorescent nitrogen-doped carbon nanodots for biological imaging and paper-based sensing

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Abstract

Green-fluorescent nitrogen-doped carbon nanodots (N-CDs) have been fabricated by hydrothermal treatment of oolong tea. The as-prepared N-CDs exhibit bright green fluorescence, excellent biocompatibility, low toxicity, and considerable optical stability. By virtue of these outstanding properties, the N-CDs have been utilized for intracellular Cu2+ imaging and paper-based Cu2+ sensing. Confocal fluorescence imaging of HepG2 cells indicates that the obtained N-CDs could visualize Cu2+ fluctuations in living cells without autofluorescence interference based on their highly selective and sensitive detection of Cu2+ ions in aqueous solution with a linear range of 0.01–75 μM and a detection limit of 2 nM. In addition, N-CD stained paper-based sensor strips have been prepared for user-friendly and convenient Cu2+ determination.

Graphical abstract: Green-fluorescent nitrogen-doped carbon nanodots for biological imaging and paper-based sensing

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Publication details

The article was received on 18 Jan 2017, accepted on 08 Mar 2017 and first published on 13 Mar 2017


Article type: Paper
DOI: 10.1039/C7AY00163K
Citation: Anal. Methods, 2017,9, 2197-2204
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    Green-fluorescent nitrogen-doped carbon nanodots for biological imaging and paper-based sensing

    L. Shi, B. Zhao, X. Li, G. Zhang, Y. Zhang, C. Dong and S. Shuang, Anal. Methods, 2017, 9, 2197
    DOI: 10.1039/C7AY00163K

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