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Microfluidic Biochip and Integrated Diffractive Optics for Bacteria Growth Control and Monitoring

Abstract

We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through diffraction optics integrated into a microfluidic chip. As an example, we demonstrate the feasibility for E. coli capture and expansion within the monolayer trap; the resulting increase in diffraction signal is consistent with the cells’ exponential growth rate.

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Publication details

The article was received on 08 Dec 2016, accepted on 20 Mar 2017, published on 20 Mar 2017 and first published online on 20 Mar 2017


Article type: Communication
DOI: 10.1039/C6AY03311C
Citation: Anal. Methods, 2017, Accepted Manuscript
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    Microfluidic Biochip and Integrated Diffractive Optics for Bacteria Growth Control and Monitoring

    C. Goh and V. Borisenko, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C6AY03311C

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