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Issue 16, 2017
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Microfluidic biochip and integrated diffractive optics for bacteria growth control and monitoring

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Abstract

We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through diffractive optics integrated into a microfluidic chip. As an example, we demonstrate the feasibility for E. coli capture and expansion within the monolayer trap; the resulting increase in the diffraction signal is consistent with the cells' exponential growth rate.

Graphical abstract: Microfluidic biochip and integrated diffractive optics for bacteria growth control and monitoring

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Publication details

The article was received on 08 Dec 2016, accepted on 20 Mar 2017 and first published on 20 Mar 2017


Article type: Communication
DOI: 10.1039/C6AY03311C
Citation: Anal. Methods, 2017,9, 2392-2396
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    Microfluidic biochip and integrated diffractive optics for bacteria growth control and monitoring

    M. C. Goh and V. Borisenko, Anal. Methods, 2017, 9, 2392
    DOI: 10.1039/C6AY03311C

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