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A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo

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Abstract

A two-photon ratiometric fluorescent probe (Mito-N) has been developed for monitoring mitochondrial nitric oxide (NO) in vivo. Mito-N exhibited excellent selectivity and sensitivity toward NO among various ROS/RNS. The successful two-photon imaging of mitochondrial NO proved that Mito-N is a powerful noninvasive imaging tool in living systems.

Graphical abstract: A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo

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Publication details

The article was received on 04 Sep 2017, accepted on 02 Nov 2017 and first published on 06 Nov 2017


Article type: Communication
DOI: 10.1039/C7AN01461A
Citation: Analyst, 2017, Advance Article
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    A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo

    X. Zhu, J. Chen, C. Ma, X. Liu, X. Cao and H. Zhang, Analyst, 2017, Advance Article , DOI: 10.1039/C7AN01461A

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