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Etching Based Fluorescent Probe for Sensitive Detection of Hydrogen Sulfide in Cells

Abstract

Hydrogen sulfide (H2S) is one of most crucial gas signaling agents mediated by many physiological and pathological processes. However, rapid high-efficiency detection and imaging of H2S in living cells is very challenging. Herein we reported a simple fluorescent nanoprobe using FAM-DNA/AgNPs nanocomposites for fast and sensitive H2S detection based on surface silver displacement. In contrast to the conventional principles for fluorescence turn-on analyte detection, the present work demonstrated a sensitive and selective AgNPs based optosensor for the assay of H2S. Compared with majority of the reported H2S probes, complex synthesis procedures and costly equipment are not involved in this assay.

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Publication details

The article was received on 22 Aug 2017, accepted on 03 Nov 2017 and first published on 03 Nov 2017


Article type: Paper
DOI: 10.1039/C7AN01394A
Citation: Analyst, 2017, Accepted Manuscript
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    Etching Based Fluorescent Probe for Sensitive Detection of Hydrogen Sulfide in Cells

    Y. Dong, L. Wang, F. Wang, N. Li, Y. Jin, J. Zhang and X. Yang, Analyst, 2017, Accepted Manuscript , DOI: 10.1039/C7AN01394A

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