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Issue 23, 2017
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A new tetraphenylethylene based AIE sensor with light-up and tunable measuring range for adenosine triphosphate in aqueous solution and in living cells

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Abstract

An AIE based tetraphenylethylene derivative (TPPTPE) was synthesized for light-up sensing of ATP in aqueous solution. The measuring range for ATP can be tuned by varying the concentration of the TPPTPE. A one-step straightforward quantitative analysis of the ATP level in cell lysates can be realized using the TPPTPE. Moreover, the TPPTPE can be used for monitoring apyrase activity in aqueous solution and detecting ATP both in living cancer cell lines and in living normal cell lines.

Graphical abstract: A new tetraphenylethylene based AIE sensor with light-up and tunable measuring range for adenosine triphosphate in aqueous solution and in living cells

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Publication details

The article was received on 11 Aug 2017, accepted on 23 Oct 2017 and first published on 26 Oct 2017


Article type: Communication
DOI: 10.1039/C7AN01336A
Citation: Analyst, 2017,142, 4388-4392
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    A new tetraphenylethylene based AIE sensor with light-up and tunable measuring range for adenosine triphosphate in aqueous solution and in living cells

    G. Jiang, W. Zhu, Q. Chen, A. Shi, Y. Wu, G. Zhang, X. Li, Y. Li, X. Fan and J. Wang, Analyst, 2017, 142, 4388
    DOI: 10.1039/C7AN01336A

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