Issue 24, 2017
From the journal:

Analyst

A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring†

M. A. Messina,*a   C. Meli,a   S. Conoci ORCID logo b  and  S. Petralia ORCID logo *b  

* Corresponding authors

a Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele, Via S. Sofia 78, Catania, Italy
E-mail: mmessina@unict.it

b STMicroelectronics, Stradale Primosole, 50-95121 Catania, Italy
E-mail: salvatore.petralia@st.com

Abstract

A miniaturized paper-based lab-on-chip (LoC) was developed for the facile measurement of urinary Phe (phenylalanine) level on PKU (Phenylketonuria) treated patient. This system permits the monitoring of Phe in a dynamic range concentration of 20–3000 μM.

Graphical abstract: A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring

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Article information

DOI
https://doi.org/10.1039/C7AN01115F
Article type
Communication
Submitted
03 Jul 2017
Accepted
28 Oct 2017
First published
31 Oct 2017

Analyst, 2017,142, 4629-4632

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A facile method for urinary phenylalanine measurement on paper-based lab-on-chip for PKU therapy monitoring

M. A. Messina, C. Meli, S. Conoci and S. Petralia, Analyst, 2017, 142, 4629 DOI: 10.1039/C7AN01115F

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