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Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

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Abstract

The selective manipulation and incubation of individual picoliter drops in high-throughput droplet based microfluidic devices still remains challenging. We used a surface acoustic wave (SAW) to induce a bubble in a 3D designed multi-trap polydimethylsiloxane (PDMS) device to manipulate multiple droplets and demonstrate the selection, incubation and on-demand release of aqueous droplets from a continuous oil flow. By controlling the position of the acoustic actuation, individual droplets are addressed and selectively released from a droplet stream of 460 drops per s. A complete trapping and releasing cycle can be as short as 70 ms and has no upper limit for incubation time. We characterize the fluidic function of the hybrid device in terms of electric power, pulse duration and acoustic path.

Graphical abstract: Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

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Publication details

The article was received on 01 Jul 2017, accepted on 16 Nov 2017 and first published on 17 Nov 2017


Article type: Paper
DOI: 10.1039/C7AN01100H
Citation: Analyst, 2018, Advance Article
  • Open access: Creative Commons BY-NC license
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    Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

    R. W. Rambach, P. Biswas, A. Yadav, P. Garstecki and T. Franke, Analyst, 2018, Advance Article , DOI: 10.1039/C7AN01100H

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