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Novel fluorescent cationic benzothiazole dye response to G-quadruplex aptamer as a novel K+ sensor

Abstract

A fluorescent cationic benzothiazole dye selectively targeting G-quadruplex aptamer was designed and synthesized as a K+ sensor. The K+-driven aptamer sensor based on the strategy of conformational transition from single-strand DNA to G-quadruplex structure and leading to an amplifying fluorescence signal of reporter. This fluorescent sensor displayed high selectivity for K+, suggesting its great potential for practical applications.

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Publication details

The article was received on 26 Jun 2017, accepted on 01 Aug 2017 and first published on 04 Aug 2017


Article type: Communication
DOI: 10.1039/C7AN01062A
Citation: Analyst, 2017, Accepted Manuscript
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    Novel fluorescent cationic benzothiazole dye response to G-quadruplex aptamer as a novel K+ sensor

    X. Sun, Q. Li, J. Xiang, L. Wang, X. Zhang, L. Lan, S. Xu, F. Yang and Y. Tang, Analyst, 2017, Accepted Manuscript , DOI: 10.1039/C7AN01062A

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