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Enzymatically activated reduction-caged SERS reporters for versatile bioassays

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Abstract

Here we report a facile strategy for activating reduction caged Raman reporters for surface-enhanced Raman scattering (SERS) with peroxidases. After selecting suitable caged reporters, versatile bioassays were developed. First, the bioassays for bioactive small molecules were developed. Then, the immunoassay was developed for C reactive protein (CRP), a biomarker for cardiovascular diseases.

Graphical abstract: Enzymatically activated reduction-caged SERS reporters for versatile bioassays

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Publication details

The article was received on 01 Apr 2017, accepted on 13 May 2017 and first published on 17 May 2017


Article type: Communication
DOI: 10.1039/C7AN00552K
Citation: Analyst, 2017, Advance Article
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    Enzymatically activated reduction-caged SERS reporters for versatile bioassays

    W. Guo, Y. Hu and H. Wei, Analyst, 2017, Advance Article , DOI: 10.1039/C7AN00552K

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