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Electrochemiluminescence Behavior of AgNCs and Its Application in Immunosensor based on PANI/PPy-Ag dendrites modified electrode

Abstract

In this paper, hyperbranched polyethyleneimine-protected silver nanoclusters (hPEI-AgNCs) with excellent electrochemiluminescence (ECL) emission in the presence of coreactant K2S2O8 was prepared by chemical reduction of silver ions (silver nitrate) coordinated with dendrigraft polymer, and successfully applied for the construction of ECL immunosensor. Polyaniline (PANI)/polypyrrole (PPy)-sliver (Ag) dendrite with good electrical conductivity and biocompatibility were electropolymerized on the surface of indium tin oxide (ITO) electrode as carriers. Porous ZnO spheres loaded hPEI-AgNCs-induced signal amplification strategies were integrated exquisitely and applied sufficiently. Taking carcinoembryonic antigen (CEA) as an example, under optimal conditions, the CEA concentration was determined in the range of 10-3 ng/mL-100 ng/mL and with a detection limit of 0.4 pg.mL-1 with this method, as well as exhibited excellent selectivity, high stability, and acceptable fabrication reproducibility. It was anticipated that hPEI-AgNCs would have promising applications in green, selective, and sensitive detection of target analytes in the future.

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Publication details

The article was received on 14 Mar 2017, accepted on 13 May 2017 and first published on 17 May 2017


Article type: Paper
DOI: 10.1039/C7AN00443E
Citation: Analyst, 2017, Accepted Manuscript
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    Electrochemiluminescence Behavior of AgNCs and Its Application in Immunosensor based on PANI/PPy-Ag dendrites modified electrode

    L. Zhang, Y. Wang, L. Shen, J. Yu, S. Ge and M. Yan, Analyst, 2017, Accepted Manuscript , DOI: 10.1039/C7AN00443E

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