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Issue 12, 2017
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Association models for binding of molecules to nanostructures

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Abstract

The interaction between nanoparticles and molecules plays a key role in determining the activity and performance of a given nanostructure. These interactions are pivotal for a variety of applications including drug delivery, surface manipulation for targeted therapies, and catalysis. However, to this day, gathering precise association parameters for the interaction of the molecules with nanostructures remains elusive and mostly imprecise. In this review, we present a critical discussion of the most commonly used techniques and models intended for determining the association of molecules with nanoparticles. Particular emphasis has been put on discussing the limitations and pitfalls related to determining association constants in this tutorial review.

Graphical abstract: Association models for binding of molecules to nanostructures

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Publication details

The article was received on 18 Feb 2017, accepted on 18 Apr 2017 and first published on 24 Apr 2017


Article type: Tutorial Review
DOI: 10.1039/C7AN00288B
Citation: Analyst, 2017,142, 2067-2089
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    Association models for binding of molecules to nanostructures

    M. Ahumada, E. Lissi, A. M. Montagut, F. Valenzuela-Henríquez, N. L. Pacioni and E. I. Alarcon, Analyst, 2017, 142, 2067
    DOI: 10.1039/C7AN00288B

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