Issue 12, 2017

Association models for binding of molecules to nanostructures

Abstract

The interaction between nanoparticles and molecules plays a key role in determining the activity and performance of a given nanostructure. These interactions are pivotal for a variety of applications including drug delivery, surface manipulation for targeted therapies, and catalysis. However, to this day, gathering precise association parameters for the interaction of the molecules with nanostructures remains elusive and mostly imprecise. In this review, we present a critical discussion of the most commonly used techniques and models intended for determining the association of molecules with nanoparticles. Particular emphasis has been put on discussing the limitations and pitfalls related to determining association constants in this tutorial review.

Graphical abstract: Association models for binding of molecules to nanostructures

Supplementary files

Article information

Article type
Tutorial Review
Submitted
18 Feb 2017
Accepted
18 Apr 2017
First published
24 Apr 2017

Analyst, 2017,142, 2067-2089

Association models for binding of molecules to nanostructures

M. Ahumada, E. Lissi, A. M. Montagut, F. Valenzuela-Henríquez, N. L. Pacioni and E. I. Alarcon, Analyst, 2017, 142, 2067 DOI: 10.1039/C7AN00288B

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