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Issue 45, 2016
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The design of a multifunctional dendrimer-based nanoplatform for targeted dual mode SPECT/MR imaging of tumors

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Abstract

A multifunctional folic acid-targeted dendrimer-based nanoplatform was designed to have both Mn(II) and 99mTc loaded via chelation. The formed nanoplatform displays good stability, cytocompatibility and hemocompatibility in a given concentration range, and can be used for targeted dual-mode single-photon emission computed tomography/magnetic resonance imaging of tumors.

Graphical abstract: The design of a multifunctional dendrimer-based nanoplatform for targeted dual mode SPECT/MR imaging of tumors

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Publication details

The article was received on 26 Aug 2016, accepted on 22 Sep 2016 and first published on 29 Sep 2016


Article type: Communication
DOI: 10.1039/C6TB02190E
Citation: J. Mater. Chem. B, 2016,4, 7220-7225
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    The design of a multifunctional dendrimer-based nanoplatform for targeted dual mode SPECT/MR imaging of tumors

    Y. Luo, L. Zhao, X. Li, J. Yang, L. Guo, G. Zhang, M. Shen, J. Zhao and X. Shi, J. Mater. Chem. B, 2016, 4, 7220
    DOI: 10.1039/C6TB02190E

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