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Issue 47, 2016
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3D printed structures for delivery of biomolecules and cells: tissue repair and regeneration

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Abstract

This paper reviews the current approaches to using 3D printed structures to deliver bioactive factors (e.g., cells and biomolecules) for tissue repair and regeneration. We discuss the benefits and critical points of potential scaffold materials and delivery strategies, particularly approaches that entail spatiotemporal variation in delivery. We also examine and critique advanced vascularization techniques, including delivery of angiogenesis factors and vascular cell sources. With further development of fabrication methods and functional materials, the 3D printed structures with embedded biomolecules and cells can be used as an effective therapeutic tool with controllable features for versatile drug delivery and tissue regeneration.

Graphical abstract: 3D printed structures for delivery of biomolecules and cells: tissue repair and regeneration

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Publication details

The article was received on 05 Jul 2016, accepted on 07 Oct 2016 and first published on 10 Oct 2016


Article type: Review Article
DOI: 10.1039/C6TB01662F
Citation: J. Mater. Chem. B, 2016,4, 7521-7539
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    3D printed structures for delivery of biomolecules and cells: tissue repair and regeneration

    J. Y. Park, G. Gao, J. Jang and D. Cho, J. Mater. Chem. B, 2016, 4, 7521
    DOI: 10.1039/C6TB01662F

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