Issue 34, 2016
From the journal:

Journal of Materials Chemistry B

Co-assembled hybrids of proteins and carbon dots for intracellular protein delivery†

Jianxu Zhang,ab   Min Zheng*c  and  Zhigang Xie ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, P. R. China
E-mail: xiez@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

c School of Chemistry and life Science, Advanced Institute of Materials Science, Changchun University of Technology, 2055 Yannan Street, Changchun, Jilin 130012, P. R. China
E-mail: zhengmin@ccut.edu.cn

Abstract

A general and simple strategy for intracellular protein delivery was developed by co-assembling carbon dots and proteins. Compared to free proteins, this delivery system can protect proteins against enzymatic hydrolysis and effectively deliver EGFP into HeLa cells.

Graphical abstract: Co-assembled hybrids of proteins and carbon dots for intracellular protein delivery

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Article information

DOI
https://doi.org/10.1039/C6TB01622G
Article type
Communication
Submitted
01 Jul 2016
Accepted
09 Aug 2016
First published
09 Aug 2016

J. Mater. Chem. B, 2016,4, 5659-5663

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Co-assembled hybrids of proteins and carbon dots for intracellular protein delivery

J. Zhang, M. Zheng and Z. Xie, J. Mater. Chem. B, 2016, 4, 5659 DOI: 10.1039/C6TB01622G

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