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Issue 42, 2016
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A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

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Abstract

A redox-responsive specific theranostic agent was developed by the conjugation of photosensitizers with the tryptophan-containing GE11 peptide via a cleavable disulfide linker. It showed a potential utility for the target-cell-specific activatable fluorescence imaging and photodynamic therapy of triple-negative breast cancers.

Graphical abstract: A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

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Publication details

The article was received on 20 Jun 2016, accepted on 11 Sep 2016 and first published on 13 Sep 2016


Article type: Communication
DOI: 10.1039/C6TB01519K
Citation: J. Mater. Chem. B, 2016,4, 6787-6790
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    A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

    J. Kim, Y. Won, S. Goh and Y. Choi, J. Mater. Chem. B, 2016, 4, 6787
    DOI: 10.1039/C6TB01519K

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