In-line holographic microscopy images of micrometer-scale fractal aggregates can be interpreted with an effective-sphere model to obtain each aggregate's size and the population-averaged fractal dimension. We demonstrate this technique experimentally using model fractal clusters of polystyrene nanoparticles and fractal protein aggregates composed of bovine serum albumin and bovine pancreas insulin.
C. Wang, F. C. Cheong, D. B. Ruffner, X. Zhong, M. D. Ward and D. G. Grier, Soft Matter, 2016, 12, 8774 DOI: 10.1039/C6SM01790H
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