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Reaction Chemistry & Engineering

Bridging the gap between chemistry and chemical engineering
Free access for 2016 and 2017

Paper

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor

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Corresponding authors
a
Institute of Process Research and Development, School of Chemistry, University of Leeds, Leeds, UK
E-mail: r.a.bourne@leeds.ac.uk
b
Department of Chemistry, Faraday Building, Lancaster University, Lancaster, UK
c
School of Chemical and Process Engineering, University of Leeds, Leeds, UK
d
AstraZeneca Pharmaceutical Development, Silk Road Business Park, Macclesfield, UK
React. Chem. Eng., 2016,1, 366-371

DOI: 10.1039/C6RE00059B
Received 17 Mar 2016, Accepted 05 May 2016
First published online 24 May 2016
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Open Access
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Supplementary Info