Jump to main content
Jump to site search

Issue 109, 2016, Issue in Progress
Previous Article Next Article

An activatable fluorescent probe with an ultrafast response and large Stokes shift for live cell bioimaging of hypochlorous acid

Author affiliations

Abstract

A novel activatable fluorescent probe for hypochlorous acid (HOCl) imaging, has been developed based on HOCl-triggered aldehyde recovery reaction. This probe features with a long emission wavelength because of the use of intramolecular charge transfer (ICT) effect in the fluorophore. Moreover, this probe displayed ultrafast response (within 1 s), good selectivity and high sensitivity (detection limit of 50 nm) toward HOCl with excellent independency upon pH of the assay system. Live cells imaging studies demonstrate that the probe can be applied successfully to detect exogenous and endogenous HOCl.

Graphical abstract: An activatable fluorescent probe with an ultrafast response and large Stokes shift for live cell bioimaging of hypochlorous acid

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Sep 2016, accepted on 10 Oct 2016 and first published on 14 Oct 2016


Article type: Paper
DOI: 10.1039/C6RA22686H
Citation: RSC Adv., 2016,6, 107910-107915
  •   Request permissions

    An activatable fluorescent probe with an ultrafast response and large Stokes shift for live cell bioimaging of hypochlorous acid

    F. Liu, Y. Tang, Y. Kuang, D. Pan, X. Liu, R. Yu and J. Jiang, RSC Adv., 2016, 6, 107910
    DOI: 10.1039/C6RA22686H

Search articles by author

Spotlight

Advertisements